2019

97) Exploiting Imine Photochemistry for Masked N‐Centered Radical Reactivity

Daryl Staveness, James L. Collins III, Rory C. McAtee, and Corey R. J. Stephenson. Angew. Chem. Int. Ed. 2019, 58, 19000-19006. Initially disclosed via ChemRxiv (DOI:10.26434/chemrxiv.7390421.v1)

Related work has been included in the following patent applications:

1) Stephenson, C.R.J.; Staveness, D. U.S. Pat. Appl. No. 62/772,302, November 28, 2018.

2) Stephenson, C.R.J.; Staveness, D. U.S. Pat. Appl. No. 62/907,881, September 30, 2019.

96) Biosynthesis of an Anti-Addiction Agent from the Iboga Plant

Scott C. Farrow, Mohamed O. Kamileen, Lorenzo Caputi, Kate Bussey, Julia E. A. Mundy, Rory C. McAtee, Corey R. J. Stephenson, and Sarah E. O’Connor. J. Am. Chem. Soc. 2019, 141, 12979.

95) Illuminating Photoredox Catalysis

Rory C. McAtee, Edward J. McClain, and Corey R. J. Stephenson. Trends in Chemistry 2019, 1, 111.

94) Selective C–O Bond Cleavage of Lignin Systems and Polymers Enabled by Sequential Palladium‐Catalyzed Aerobic Oxidation and Visible Light Photoredox Catalysis

Gabriel Magallanes, Markus D. Kärkäs, Irene Bosque, Sudarat Lee, Stephen Maldonado, and Corey R. J. Stephenson. ACS Catalysis 2019, 9, 2252.

93) Advancements in Visible-Light-Enabled Radical C(sp)2–H Alkylation of (Hetero)arenes

Alexandra C. Sun, Rory C. McAtee, Edward J. McClain, and Corey R. J. Stephenson. Synthesis 2019, 51, 1063.

92) Providing a New Aniline Bioisostere through the Photochemical Production of 1-Aminonorbornanes

Daryl Staveness, Taylor M. Sodano, Kangjun Li, Elizabeth A. Burnham, Klarissa D. Jackson, Corey R. J. Stephenson. Chem 2019, 5, 215. Initially disclosed via ChemRxiv (DOI:10.26434/chemrxiv.5437255.v1)

Publications 2009-2000: CV

2018

91) Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, ..., Corey R. J. Stephenson, ..., and Jason M. Rohde. ACS Cent. Sci. 2018, 4, 1727.

This work included contributions from 45 academic research groups across the United States. Follow this link for a complete author list.

90) Exploiting Imine Photochemistry for Masked N-Centered Radical Reactivity

Daryl Staveness, James L. Collins III, Rory C. McAtee, and Corey R. J. Stephenson. ChemRxiv 2018. DOI:10.26434/chemrxiv.7390421.v1

89) Electrochemical Dimerization of Phenylpropenoids and the Surprising Antioxidant Activity of the Resultant Quinone Methide Dimers

Kevin J. Romero, Matthew S. Galliher, Mark A. R. Raycroft, Jean-Philippe R. Chauvin, Irene Bosque, Derek A. Pratt, and Corey R. J. Stephenson. Angew. Chem. Int. Ed. 2018, 57, 17125.

88) Arylsulfonylacetamides as bifunctional reagents for alkene aminoarylation

Timothy M. Monos, Rory C. McAtee, and Corey R. J. Stephenson. Science 2018, 361, 1369. Highlighted in Nachrichten aus der Chemie.

87) Radicals in natural product synthesis

Kevin J. Romero, Matthew S. Galliher, Derek A. Pratt, and Corey R. J. Stephenson. Chem. Soc. Rev. 2018, 47, 7851.

86) Visible light mediated aryl migration by homolytic C-N cleavage of aryl amines

Dirk Alpers, Kevin Cole, and Corey Stephenson, Angew. Chem. Int. Ed. 2018, 57, 12167.

85) Visible Light-Mediated Decarboxylative Alkylation of Pharmaceutically Relevant Heterocycles

Alexandra C. Sun, Edward J. McClain, Joel W. Beatty, and Corey R. J. Stephenson. Org. Lett. 2018, 20, 3487.

84) Radical Chlorodifluoromethylation: Providing a Motif for (Hetero)arene Diversification

Rory C. McAtee, Joel W. Beatty, Christopher C. McAtee, and Corey R. J. Stephenson. Org. Lett. 2018, 20, 3491.

83) Lithium bis-catechol borate as an effective reductive quencher in photoredox catalysis

Martin J. Sevrin, Laura Furst, John D. Nguyen, James L. Collins III, and Corey R. J. Stephenson. Tetrahedron 2018, 74, 3246.

Publications 2009-2000: CV

2017

82) Redox Catalysis Facilitates Lignin Depolymerization

Irene Bosque, Gabriel Magallanes, Mathilde Rigoulet, Markus D. Kärkäs, and Corey R. J. Stephenson, ACS Cent. Sci. 2017, 3, 621. Highlighted in Synform.

Publications 2009-2000: CV

2016

81) Synthesis of Resveratrol Tetramers via a Stereoconvergent Radical Equilibrium.

Mitchell H. Keylor, Bryan S. Matsuura, Markus Griesser, Jean-Philippe R. Chauvin, Ryan A. Harding, Mariia S. Kirillova, Xu Zhu, Oliver J. Fischer, Derek A. Pratt and Corey R. J. Stephenson, Science 2016, 354, 1260. Highlighted in C&E News.

80) Photocatalytic Oxidation of Lignin Model Systems by Merging Visible-Light-Induced Photoredox and Palladium Catalysis.

Markus D. Kärkäs, Irene Bosque, Bryan S. Matsuura and Corey R. J. Stephenson, Org. Lett. 2016, 18, 5166.

79) Free Radical Chemistry Enabled by Visible Light-Induced Electron Transfer.

Daryl Staveness, Irene Bosque and Corey R. J. Stephenson, Acc. Chem. Res. 2016, 49, 2295. Published as part of the special Issue on Photoredox Catalysis in Organic Chemistry.

78) Photochemical Perfluoroalkylation with Pyridine N-Oxides: Mechanistic Insights and Performance on Kilogram Scale.

Joel W. Beatty, James J. Douglas, Richard Miller, Rory McAtee, Kevin P. Cole and Corey R. J. Stephenson, Chem 2016, 1, 456. Highlighted in C&E News.

77) Light-Mediated Reductive Debromination of Unactivated Alkyl and Aryl Bromides.

James J. Devery, John D. Ngyuen, Chunhui Dai and Corey R. J. Stephenson, ACS Catalysis 2016, 6, 5962.

76) Visible light photocatalysis: applications and new disconnections in the synthesis of pharmaceutical agents.

James J. Douglas, Martin J. Sevrin and Corey R. J. Stephenson, Org. Proc. Res. Dev. 2016, 20, 1134.

75) Preparative Scale Demonstration and Mechanistic Investigation of a Visible Light-Mediated Radical Smiles Rearrangement.

James J. Douglas, Martin J. Sevrin, Kevin P. Cole and Corey R. J. Stephenson, Org. Proc. Res. Dev. 2016, 20, 1148.

74) Microwave-assisted synthesis of heteroleptic Ir(III)+ polypyridyl complexes.

Timothy M. Monos, Alexandra C. Sun, Rory C. McAtee, James J. Devery, III and Corey R. J. Stephenson, J. Org. Chem. 2016, 81, 6988. Selected as a Featured Article for the Special issue on Photocatalysis.

73) Visible Light Mediated Reductions of Ethers, Amines, and Sulfides

Timothy M. Monos, Gabriel Magallanes, Leanne J. Sebren and Corey R. J. Stephenson, J. Photochem. Photobiol. A 2016, 328, 240. Invited feature article.

72) Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis

Markus D. Kärkäs, John. A. Porco, Jr. and Corey R. J. Stephenson, Chem. Rev. 2016, 116, 9683. Published a part of the special issue on Photochemistry in Organic Synthesis.

71) Formation and trapping of azafulvene intermediates derived from manganese-mediated oxidative malonate coupling.

Verner A. Lofstrand, Bryan S. Matsuura, Laura Furst, Jagan M. R. Narayanam and Corey R. J. Stephenson, Tetrahedron 2016, 72, 3775. Published a part of the special issue in honor of Professor Neil Garg for his receipt of the Tetrahedron Young Investigator Award.

70) Transition-metal catalyzed valorization of lignin: the key to a sustainable carbon-neutral future.

Markus D. Kärkäs, Bryan S. Matsuura, Timothy Monos, Gabriel Magallanes and Corey R. J. Stephenson, Org. Biomol. Chem. 2016, 14, 1853.

69) Intermolecular Photocatalytic C-H Functionalization of Electron-Rich Heterocycles with Tertiary Alkyl Halides.

Elizabeth C. Swift, Theresa M. Williams and Corey R. J. Stephenson, Synlett 2016, 27, 754. Published in the special cluster of articles on modern radical chemistry.

Publications 2009-2000: CV

2015

68) A Visible Light-Mediated Radical Smiles Rearrangement and its Application to the Synthesis of a Difluorospirocyclic ORL-1 Antagonist.

James J. Douglas, H. Albright, Martin J. Sevrin, Kevin P. Cole and Corey R. J. Stephenson, Angew. Chem. Int. Ed. 2015, 54, 14898.

67) Enchained by visible light-mediated photoredox catalysis.

Markus D. Kärkäs, Bryan S. Matsuura and Corey R. J. Stephenson, Science, 2015, 349, 1285. (Perspective Article)

66) A scalable and operationally simple radical trifluoromethylation.

Joel W. Beatty, James J. Douglas, Kevin P. Cole and Corey R. J. Stephenson, Nature Comm. 2015, 6, 7919. PMCID: PMC4533119.

65) Amine functionalization via oxidative photoredox catalysis: Methodology development and complex molecule synthesis.

Joel W. Beatty and Corey R. J. Stephenson, Acc. Chem. Res. 2015, 48, 1474. PMCID: PMC4440623. Invited contribution for the Synthesis, Design, and Molecular Function Special Issue.

64) Dual catalysis at the flick of a switch.

James J. Devery, III and Corey R. J. Stephenson, Nature, 2015, 519, 42. (News and Views article)

63) The chemistry and biology of resveratrol-derived natural products

Mitchell H. Keylor, Bryan S. Matsuura and Corey R. J. Stephenson, Chem. Rev. 2015, 115, 8976. PMCID: PMC4566929. Published in the Frontiers in Organic Synthesis Special Issue.

62) A Scalable Biomimetic Synthesis of Resveratrol Dimers and Systematic Evaluation of their Antioxidant Activities.

Bryan S. Matsuura, Mitchell H. Keylor, Bo Li, YuXuan Lin, Shelby Allison, Derek A. Pratt* and Corey R. J. Stephenson* Angew. Chem. Int. Ed. 2015, 54, 3754. This article was selected as a Hot Paper by the editors of Angewandte Chemie and highlighted in Nature Chemistry and Synfacts.

61) Ligand Functionalization as a Deactivation Pathway in a fac -Ir(ppy)3 -Mediated Radical Addition.

James J. Devery, III, James J. Douglas, John D. Nguyen, Kevin P. Cole, Robert A. Flowers, II and Corey R. J. Stephenson, Chem. Sci. 2015, 6, 537.

Publications 2009-2000: CV

2014

60) Photoredox Catalysis in a Complex Pharmaceutical Setting: Toward the Preparation of JAK2 Inhibitor LY2784544.

James J. Douglas, Kevin P. Cole, and Corey R. J. Stephenson, J. Org. Chem. 2014, 79, 11631. This paper was highlighted in OPRD and Synfacts.

59) Synthesis of (-)-Pseudotabersonine, (-)-Pseudovincadifformine, and (+)-Coronaridine Enabled by Photoredox Catalysis in Flow.

Joel W. Beatty and Corey R. J. Stephenson, J. Am. Chem. Soc. 2014, 136, 10270. This paper was selected as a JACS spotlight article.

58) Photocatalytic initiation of thiol-ene reactions: Synthesis of thiomorpholin-3-ones.

Mitchell H. Keylor, James E. Park, Carl-Johan Wallentin and Corey R. J. Stephenson, Tetrahedron 2014, 70, 4264. Special issue in honor of Tetrahedron Young Investigator Professor Sarah Reisman

57) Enabling Novel Photoredox Reactivity via Photocatalyst Selection.

James J. Douglas, John D. Nguyen, Kevin P. Cole and Corey R. J. Stephenson, Aldrichimica Acta 2014, 47, 15

56) The Development of Visible Light Photoredox Catalysis in Flow.

Zachary J. Garlets, John D. Nguyen and Corey R. J. Stephenson, Isr. J. Chem. 2014, 54, 351. PMCID: PMC4255365. Special issue on "Flow Chemistry Concepts & Applications"

55) Light-Assisted Cross Dehydrogenative Coupling Reactions.

Laura Furst and Corey R. J. Stephenson, In Carbon-carbon Bond Formations via Cross-Dehydrogenative-Coupling of C-H Bonds; Li, C.-J., Ed.; Royal Society of Chemistry.

54) A Photochemical Strategy for Lignin Degradation at Room Temperature.

John D. Nguyen, Bryan S. Matsuura and Corey R. J. Stephenson, J. Am. Chem. Soc. 2014, 136, 1218.

53) Catalytic Radical Domino Reactions in Organic Synthesis

Leanne J. Sebren, James J. Devery, III and Corey R. J. Stephenson, ACS Catalysis 2014, 4, 703. PMCID: PMC3935257.

52) Photoredox Activation and Anion Binding Catalysis in the Dual Catalytic Enantioselective Synthesis of b -Amino Esters.

Giulia Bergonzini, Corinna S. Schindler, Carl-Johan Wallentin, Eric N. Jacobsen and Corey R. J. Stephenson Chem. Sci. 2014, 5, 112. PMCID: PMC3842187.

51) Ruthenium(II), Tris(1,10-phenanthroline-kN1,kN10)-dichloride.

Joel W. Beatty and Corey R. J. Stephenson, eEROS In Press

Publications 2009-2000: CV

2013

50) The renaissance of organic radical chemistry - deja vu all over again.

Corey R. J. Stephenson, Armido Studer and Dennis P. Curran Beil. J. Org. Chem. 2013, 9, 2778.

49) Tandem Dienone Photorearrangement–Cycloaddition for the Rapid Generation of Molecular Complexity.

Pieter H. Bos, Mitchell T. Antalek, John A. Porco, Jr., and Corey R. J. Stephenson, J. Am. Chem. Soc. 2013, 135, 17978. PMCID: PMC3964885

48) Batch to Flow Deoxygenation Using Visible Light Photoredox Catalysis.

John D. Nguyen, Barbara Reiss, Chunhui Dai and Corey R. J. Stephenson, Chem. Commun. 2013, 49, 4352. ChemComm Emerging Investigators Issue 2013

Publications 2009-2000: CV

2012

47) Engaging Unactivated Alkyl, Alkenyl and Aryl iodides in Visible-Light Mediated Free Radical Reactions.

John D. Nguyen, Erica M. D'Amato, Jagan M. R. Narayanam and Corey R. J. Stephenson, Nature Chem. 2012, 4, 854

46) Radical Carbon-Carbon Bond Formations Enabled by Visible Light Active Photocatalysts.

Carl-Johan Wallentin, John D. Nguyen and Corey R. J. Stephenson, Chimia, 2012, 66, 394. Special issue for the 11th International Symposium on Organic Free Radicals, Berne, Switzerland

45) Expanding the Chemical Diversity of Spirooxindoles via Alkylative Pyridine Dearomatization.

Chunhui Dai, Bo Liang and Corey R. J. Stephenson, Beilstein J. Org. Chem. 2012, 8, 986 Special issue on chemical diversity.

44) Visible Light-Mediated Atom Transfer Radical Addition via Oxidative and Reductive Quenching of Photocatalysts.

Carl-Johan Wallentin, John D. Nguyen, Peter Finkbeiner and Corey R. J. Stephenson, J. Am. Chem. Soc. 2012, 134, 8875. This paper was one of the most accessed articles in May/June.

43) Synthesis of Symmetric Anhydrides Using Visible Light-Mediated Photoredox Catalysis.

Marlena D. Konieczynska, Chunhui Dai and Corey R. J. Stephenson, Org. Biomol. Chem. 2012, 10, 4509. Invited contribution to a special web themed issue on organocatalysis. This paper was selected as a Hot article by the editors.

42) Friedel-Crafts Amidoalkylation via Thermolysis and Oxidative Photocatalysis.

Chunhui Dai, Francesco Meschini, Jagan M.R. Narayanam and Corey R. J. Stephenson, J. Org. Chem. 2012, 77, 4425. This note was one of the most accessed articles in April.

41) Visible Light Photoredox Catalysis in Flow.

Joseph W. Tucker, Yuan Zhang, Timothy F. Jamison and Corey R. J. Stephenson, Angew. Chem., Int. Ed. 2012, 51, 4144. This article was selected by the editors as a Hot Paper.

40) Shining Light on Photoredox Catalysis: Theory and Synthetic Applications.

Joseph W. Tucker and Corey R. J. Stephenson, J. Org. Chem. 2012, 77, 1617. This synopsis was one of the most accessed articles in January and in the past 12 months.

39) Functionally Diverse Nucleophilic Trapping of Iminium Intermediates Generated Utilizing Visible Light Photoredox Catalysis.

David B. Freeman, Laura Furst, Allison G. Condie and Corey R. J. Stephenson, Org. Lett. 2012, 14, 94. This paper was one of the most accessed articles in December.

Publications 2009-2000: CV

2011

38) Intercepting Wacker Intermediates with Arenes: C-H Functionalization and Dearomatization.

Bryan S. Matsuura, Allison G. Condie, Ian A. McBee, Ryan C. Buff, Gregory J. Karahalis and Corey R. J. Stephenson, Org. Lett. 2011, 13, 6320.

37) Tandem Visible Light-Mediated Radical Cyclization-Divinylcyclopropane Rearrangement to Tricyclic Pyrrolidinones.

Joseph W. Tucker and Corey R. J. Stephenson, Org. Lett. 2011, 13, 5468. PMID: 21939250

36) Ruthenium(II), tris(2,2'-bipyridine-kN1,kN1')-dichloride.

Laura Furst and Corey R. J. Stephenson, eEROS In press.

35) Reaction design: Nature-inspired total synthesis.

Laura Furst and Corey R. J. Stephenson, News and Views in Nat. Chem. Bio. 2011, 7, 582.

34) Total Synthesis of (+)-Gliocladin C Enabled by Visible Light Photoredox Catalysis.

Laura Furst, Jagan M. R. Narayanam and Corey R. J. Stephenson, Angew. Chem., Int. Ed. 2011, 50, 9655. This paper was highlighted in Chemistry World and Synfacts and was selected as a Very Important Article by the editors. PMID: 21751318

33) Oxidative Photoredox Catalysis: Mild and Selective Deprotection of PMB Ethers Mediated by Visible Light.

Joseph W. Tucker, Jagan M. R. Narayanam, Pinkey S. Shah and Corey R. J. Stephenson, Chem. Commun. 2011, 47, 5040. PMID: 21431223

32) Intermolecular Atom Transfer Radical Addition to Olefins Mediated by Oxidative Quenching of Photoredox Catalysts.

John D. Nguyen, Joseph W. Tucker, Marlena D. Konieczynska and Corey R. J. Stephenson, J. Am. Chem. Soc. 2011, 133, 4160. PMID: 21381734

31) Visible Light Mediated Conversion of Alcohols to Halides.

Chunhui Dai, Jagan M. R. Narayanam and Corey R. J. Stephenson, Nature Chem. 2011, 3, 140. This paper was highlighted in Chemistry World and TCE today and featured as a SynStory in SynForm. PMID: 21258387

30) Visible Light Photoredox Catalysis: Applications in Organic Synthesis.

Jagan M. R. Narayanam and Corey R. J. Stephenson, Chem. Soc. Rev. 2011, 40, 102. Invited Review PMID: 20532341

Publications 2009-2000: CV

2010

29) Total Synthesis of Syringolin A.

Chunhui Dai and Corey R. J. Stephenson, Org. Lett. 2010, 12, 3453. This paper was one of the most accessed articles in July and in 2010. PMID: 20597471

28) Visible Light Photoredox Catalysis: Intermolecular C-H Functionalization of Electron-Rich Heterocycles with Malonates.

Laura Furst, Bryan S. Matsuura, Jagan M. R. Narayanam, Joseph W. Tucker and Corey R. J. Stephenson, Org. Lett. 2010, 12, 3104. PMID: 20518528

27) Tin-Free Radical Cyclization Reactions Initiated by Visible Light Photoredox Catalysis.

Joseph W. Tucker, John D. Nguyen, Jagan M. R. Narayanam, Scott W. Krabbe and Corey R. J. Stephenson, Chem. Commun. 2010, 46, 4985. PMID: 20512181

26) Visible Light Photoredox Catalysis: Aza-Henry Reactions via C-H Functionalization.

Allison G. Condie, Jose-Carlos González-Gómez and Corey R. J. Stephenson, J. Am. Chem. Soc. 2010, 132, 1464. PMID: 20070079

25) Multicomponent Reaction Discovery: Three-Component Synthesis of Spirooxindoles.

Bo Liang, Srinivas Kalidindi, John A. Porco Jr. and Corey R. J. Stephenson, Org. Lett. 2010, 12, 572. PMID: 20050598

24) Electron-Transfer Photoredox Catalysis: Intramolecular Radical Addition to Indoles and Pyrroles.

Joseph W. Tucker, Jagan M. R. Narayanam, Scott W. Krabbe and Corey R. J. Stephenson, Org. Lett. 2010, 12, 368. PMID: 20014770

Publications 2009-2000: CV

2009

23) Electron-Transfer Photoredox Catalysis: Development of a Tin-Free Reductive Dehalogenation Reaction.

Jagan M. R. Narayanam, Joseph W. Tucker and Corey R. J. Stephenson, J. Am. Chem. Soc. 2009, 131, 8756. This paper was highlighted in C&E News and Angewandte Chemie and was one of the most read articles in June. PMID: 19552447

Publications 2009-2000: CV